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Genetic diagnosis. Implications for medical practice.

D Blumenthal, R Zeckhauser

    International Journal of Technology Assessment in Health Care
    |January 1, 1989
    PubMed
    Summary

    Genetic diagnostics enable early disease predisposition detection, transforming medicine into a predictive science. This impacts healthcare organization, financing, insurance, and preventive medicine strategies.

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    Area of Science:

    • Medical Genetics
    • Health Services Research
    • Preventive Medicine

    Background:

    • Advancements in genetic diagnostics allow for early identification of disease predispositions.
    • Medicine is evolving towards a predictive model alongside diagnostic and therapeutic approaches.
    • Genetic information has significant implications for various healthcare facets.

    Purpose of the Study:

    • To examine the potential effects of new genetic diagnostics on healthcare organization and financing.
    • To illustrate these effects using genetic predisposition tests for Reye's Syndrome and lung cancer in smokers.

    Main Methods:

    • Review of current and emerging genetic diagnostic technologies.
    • Analysis of potential impacts on healthcare system components.
    • Case study analysis of specific genetic tests (Reye's Syndrome, lung cancer in smokers).

    Main Results:

    • Genetic diagnostics may reshape preventive medicine's role and effectiveness.
    • Potential shifts in competitive dynamics among healthcare organizations and insurers.
    • Impacts on insurance access and the gatekeeping role of primary care physicians.

    Conclusions:

    • Genetic diagnostics necessitate a re-evaluation of healthcare organization and financing models.
    • Proactive adaptation to genetic information is crucial for future healthcare delivery.
    • The integration of predictive genetic testing requires careful consideration of ethical and logistical challenges.

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