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Physical activity and cardiovascular risk factors in children: meta-analysis of randomized clinical trials

Claudia Ciceri Cesa1, Graciele Sbruzzi2, Rodrigo Antonini Ribeiro3

  • 1Instituto de Cardiologia do Rio Grande do Sul/Fundação Universitária de Cardiologia, Avenida Princesa Isabel, 370/3 andar. Porto Alegre, Rio Grande do Sul 90620-000, Brazil.

Preventive Medicine
|September 2, 2014
PubMed

Insights

Physical activity interventions for children aged 6-12 years did not significantly reduce BMI but did lower blood pressure and triglycerides. These programs are recommended for cardiovascular disease prevention in schoolchildren.

Area of Science:

  • Pediatrics
  • Cardiovascular Health
  • Exercise Science

Background:

  • Childhood cardiovascular risk factors are a growing concern.
  • Early intervention is crucial for long-term health.
  • Physical activity is a key lifestyle component for children's well-being.

Purpose of the Study:

  • To systematically review and meta-analyze randomized clinical trials (RCTs).
  • To assess the impact of physical activity interventions on childhood cardiovascular risk factors.
  • To evaluate effects on body mass index (BMI), blood pressure (BP), and lipid profiles.

Main Methods:

  • Systematic review and meta-analysis of RCTs.
  • Searched PubMed, EMBASE, and Cochrane CENTRAL databases.
  • Included RCTs involving children aged 6-12 years with interventions >6 months.

Main Results:

  • 11 RCTs (10,748 subjects) were included.
  • No significant reduction in BMI observed.
  • Significant reductions in systolic blood pressure, diastolic blood pressure, and triglycerides were found.
  • A slight increase in total cholesterol was noted.

Conclusions:

  • Physical activity interventions >6 months are associated with reduced blood pressure and triglycerides in children.
  • These programs show promise for cardiovascular disease prevention in schoolchildren.
  • Integration into school-based prevention strategies is recommended.
Abstract

Keywords:
Blood pressureChildExerciseLipidsMotor activityObesity

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