Related Experiment Video
Updated: Apr 25, 2026

Manufacture and Drug Delivery Applications of Silk Nanoparticles
Published on: October 8, 2016
Enhanced delivery of nano- and submicron particles using elongated microparticles
Anthony P Raphael, John P Sisney, David C Liu
1Dermatology Research Centre, The University of Queensland, School of Medicine, Level 5 West Wing, Translational Research Institute, 37 Kent Street, Woolloongabba, Brisbane, QLD 4102, Australia. t.prow@uq.edu.au.
Abstract:
Nanodermatology is a rapidly emerging field of study receiving significant interest because of its potential application in the prevention and treatment of skin diseases. However, nanoparticulate penetration into and through the skin is not feasible through topical application alone. Many physical and chemical approaches have been developed to enhance particulate penetration into skin. The most successful have been physical penetration enhancers. We have found that elongated microparticles can significantly improve topical nano- and microsphere delivery in an in vivo porcine model. The delivery efficiency was inversely related to the diameter of the payload. These data support a role for elongated microparticle enhanced delivery of nano- and submicron particulate cosmeceutical or therapeutic applications.
More Related Videos
10:12Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles
Published on: January 7, 2019
10:16Targeted Plasma Membrane Delivery of a Hydrophobic Cargo Encapsulated in a Liquid Crystal Nanoparticle Carrier
Published on: February 8, 2017
Related Concept Videos
Factors Affecting Dissolution: Particle Size and Effective Surface Area
Site-Targeted Drug Delivery Systems: Polymeric Carriers