Related Experiment Video
Updated: Apr 24, 2026

07:54
Heterogeneity Mapping of Protein Expression in Tumors using Quantitative Immunofluorescence
Published on: October 25, 2011
20.3K
Breast carcinomas: variations in sonoelastographic appearance
Eduardo de Faria Castro Fleury1, Maria do Carmo Guedes Alcoforado Assunção-Queiros2, Decio Roveda1
1Faculdade de Cências Médicas da Santa Casa de São Paulo, São Paulo, Brazil.
Breast Cancer (Dove Medical Press)
|September 2, 2014
Summary
Sonoelastography accurately identifies breast cancer histology, with false-negative results linked to lesion type, not size or age. This imaging technique aids in breast carcinoma diagnosis.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Breast carcinoma diagnosis relies on imaging and biopsy.
- Sonoelastography is an emerging tool for assessing breast lesion stiffness.
Purpose of the Study:
- To evaluate factors influencing sonoelastography findings in breast carcinoma.
- To correlate sonoelastographic scores with histopathologic results.
Main Methods:
- Prospective study of 540 breast lesions in women.
- 84 carcinomas analyzed with sonoelastography and classified by score.
- Histopathologic analysis categorized lesions as soft or hard.
Main Results:
- Sonoelastography yielded 9 false-negative and 75 true-positive results.
- Correlation found between sonoelastographic scores and lesion histology.
- No significant differences noted for patient age or lesion diameter.
Conclusions:
- Sonoelastography presentation is associated with breast lesion histology.
- Histologic type, not size or age, influences false-negative sonoelastography results.

