Related Experiment Video
Updated: Apr 24, 2026

Combined Supine and Standing Imaging for Varicocele: An Improved Diagnostic Approach
Published on: November 22, 2024
Children and adults varicocele: diagnostic issues and therapeutical strategies
Massimo Valentino1, Michele Bertolotto2, Lorenzo Derchi3
1Radiology Unit, S. Antonio Hospital, via Morgagni 18, 33028 Tolmezzo (Udine), Italy.
Insights
Varicocele, or dilated scrotal veins, affects 15% of men and causes male infertility. Color-Doppler ultrasonography (US) is the preferred diagnostic tool for varicocele, guiding treatment decisions.
Area of Science:
- Urology
- Radiology
- Andrology
Background:
- Varicocele, characterized by abnormally dilated scrotal veins, affects 15% of the general male population and up to 40% of infertile males.
- The pathophysiology of varicocele remains incompletely understood, leading to challenges in establishing definitive diagnostic criteria and treatment indications for asymptomatic individuals.
- Accurate assessment of testicular volume, vein diameter, and testicular growth in adolescents is crucial, with ultrasonography (US) being the optimal method.
Purpose of the Study:
- To review the diagnostic utility of ultrasonography, particularly color-Doppler US, in the detection and classification of varicocele.
- To discuss the current understanding of varicocele pathophysiology and its implications for diagnosis and treatment.
- To evaluate the effectiveness of various varicocele treatment modalities and their associated outcomes.
Main Methods:
- Review of existing literature on varicocele diagnosis and treatment.
- Emphasis on the role of ultrasonography (US) and color-Doppler US in varicocele assessment.
- Analysis of different surgical and radiological treatment techniques.
Main Results:
- Color-Doppler US is the method of choice for detecting spermatic vein reflux and grading varicoceles.
- Color-Doppler US and spectral analysis are effective non-invasive methods for detecting subclinical varicocele linked to infertility.
- No consensus exists regarding the most effective treatment technique (open surgery, laparoscopy, interventional radiology) for varicocele.
Conclusions:
- Color-Doppler US is a reliable and accessible method for diagnosing and classifying varicoceles caused by venous reflux.
- Varicocelectomy plays a significant role in managing adult male infertility associated with varicocele.
- Further research is needed to clarify pathophysiology and standardize treatment guidelines.
Abstract:
Varicocele is defined as abnormally dilated scrotal veins. It is present in 15 % of normal males and in 40 % of males with infertility. This disorder is a challenge for the physicians involved in the diagnosis and treatment, as the pathophysiology of varicocele is not yet completely understood. For this reason, accurate diagnostic criteria and clear indications for treatment in asymptomatic adolescents or adults with clinical or subclinical varicocele are still not defined. Ultrasonography (US) is considered the best method for calculating the volume of the testicles, measuring vein diameter and monitoring the growth of the testis in adolescent patients. Color-Doppler US is the method of choice for detecting spermatic vein reflux and for classifying the grade of varicocele. Various classification systems have been published with recommendations on how to perform US imaging of the scrotum. Currently, color-Doppler US and spectral analysis are the most effective, non-invasive diagnostic procedures as they allow detection of subclinical varicocele associated with infertility. Various techniques are used in the treatment of varicocele including open surgery, laparoscopic procedures and interventional radiology. However, there is no consensus among physicians on which technique is the most effective in terms of outcome and complication rates. This review shows that color-Doppler US is currently the most widely employed diagnostic method for detection and classification of varicocele caused by venous reflux, as it is reliable and easily performed. The review also highlights the role of varicocelectomy in the management of adult male infertility.
Related Concept Videos
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Venous Thrombosis III: Interprofessional Care
Varicose Veins I: Introduction

