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[Myocardial deformation and rotation in hypertensive men with different degrees of left ventricular hypertrophy]

G V Dziak, M Iu Kolesnik

    Kardiologiia
    |September 2, 2014
    PubMed

    Insights

    Hypertension impacts myocardial deformation even before left ventricular hypertrophy (LVH) develops. Early assessment of LV remodeling is possible by observing changes in myocardial deformation, which correlate with LVH severity.

    Area of Science:

    • Cardiology
    • Biomedical Engineering
    • Medical Imaging

    Context:

    • Hypertension is a major risk factor for cardiovascular disease.
    • Left ventricular hypertrophy (LVH) is a common complication of untreated hypertension.
    • Early detection of cardiac changes in hypertensive patients is crucial for timely intervention.

    Purpose:

    • To evaluate myocardial deformation and rotation in untreated hypertensive men.
    • To determine the relationship between the presence and degree of LVH and myocardial mechanics.
    • To investigate early signs of cardiac remodeling in hypertension.

    Summary:

    • 98 untreated hypertensive men underwent clinical evaluation, echocardiography, and ambulatory blood pressure monitoring.
    • Two-dimensional speckle tracking echocardiography assessed left ventricular (LV) deformation and rotation.
    • Reduced longitudinal strain was observed even in hypertensive patients without LVH, with worsening deformation and increased apical rotation in severe LVH.

    Impact:

    • Demonstrates that myocardial deformation changes occur in hypertension prior to overt LVH.
    • Suggests potential for early assessment of LV remodeling using deformation parameters.
    • Highlights the correlation between the degree of LVH and alterations in myocardial mechanics.
    Abstract

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