Diverticulitis in the young

Kunut Kijsirichareanchai1, Charoen Mankongpaisarnrung2, Grerk Sutamtewagul2

  • 1University of Nebraska Medical Center, Omaha, NE, USA Texas Tech University Health Sciences Center, Lubbock, TX, USA k.kijsirichareanchai@unmc.edu.

Insights

Colonic diverticulitis is uncommon in young adults, particularly Hispanic men. This study found younger patients were more likely to be discharged from the emergency department, but long-term outcomes require further investigation.

Area of Science:

  • Gastroenterology
  • Clinical Medicine
  • Epidemiology

Background:

  • Colonic diverticulitis is rare in patients under 40.
  • Comparison of young patients (≤40) versus older patients (>40) with diverticulitis is needed.

Purpose of the Study:

  • To compare demographic data, clinical presentation, management, and clinical course of diverticulitis in patients ≤40 years old versus patients >40 years old.
  • To identify specific characteristics of diverticulitis in younger populations.

Main Methods:

  • Retrospective study of patients diagnosed with diverticulitis between October 2009 and September 2010.
  • Patients divided into two groups: ≤40 years old and >40 years old.
  • Comparison of demographic characteristics, clinical presentation, management, and short-term outcomes.

Main Results:

  • A higher proportion of obese and Hispanic men were in the younger group (≤40).
  • Younger patients had a significantly higher emergency department discharge rate (56.8% vs 7.0%).
  • No significant differences were observed in vital signs, laboratory data, or in-hospital mortality between groups.

Conclusions:

  • Young Hispanic men are a demographic that develops diverticulitis.
  • Diverticulitis should be considered in young patients presenting with abdominal symptoms.
  • Further longitudinal studies are necessary to understand long-term outcomes and pathogenesis in young patients.
Abstract

Related Concept Videos

Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
23
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
4.3K
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
20
Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
22
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
83
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
1.5K