Related Experiment Video
Updated: Apr 24, 2026

Sulfate Separation by Selective Crystallization with a Bis-iminoguanidinium Ligand
Published on: September 8, 2016
Keratan sulfate: an up-to-date review
1Program of Glycobiology, Institute of Medical Biochemistry Leopoldo de Meis, and University Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro, Rio de Janeiro, RJ 21941-913, Brazil.
Abstract:
Keratan sulfate (KS) is a glycosaminoglycan (GAG) type consisted of a sulfated poly-N-acetyl lactosamine chain. Besides acting as a constitutive molecule of the extracellular matrices, this GAG also plays a role as a hydrating and signaling agent in cornea and cartilage tissues. Inasmuch, KS is widely explored in the pharmaceutical industry. This review will cover the major achievements described in the literature of 2010-2014 concerning this GAG. Discussion about KS' roles in physiopathological conditions, as target or therapeutic molecule in diseases, methods of analysis and detection as well as KS-related enzymes, metabolism and developmental biology is properly provided.
Related Concept Videos
Preparation and Reactions of Sulfides
Sulfate Attack on Concrete
Sulfates from sources like soil, groundwater, or industrial effluents...
Phase II Reactions: Sulfation and Conjugation with α-Amino Acids
Structure and Nomenclature of Thiols and Sulfides
Sulfur Assimilation
Electrophilic Aromatic Substitution: Sulfonation of Benzene

