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Updated: Apr 24, 2026
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Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor
Published on: February 10, 2014
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Combined optical and electronic sensing of epithelial cells using planar organic transistors
Marc Ramuz1, Adel Hama, Miriam Huerta
1Department of Bioelectronics, Ecole Nationale Supérieure des Mines CMP-EMSE, MOC, 880 avenue de Mimet, 13541, Gardanne, France.
Advanced Materials (Deerfield Beach, Fla.)
|September 3, 2014
Abstract:
A planar, conducting-polymer-based transistor for combined optical and electronic monitoring of live cells provides a unique platform for monitoring the health of cells in vitro. Monitoring of MDCK-I epithelial cells over several days is shown, along with a demonstration of the device for toxicology studies, of use in future drug discovery or diagnostics applications.
Keywords:
MDCK cellsbarrier tissueconducting polymerspoly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS)tight junctions
