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Published on: March 14, 2020
Cephalexin induced cholestatic jaundice
Abhinav Agrawal1, Mana Rao1, Sarfaraz Jasdanwala1
1Department of Internal Medicine, Monmouth Medical Center, Long Branch, NJ 07740, USA.
Abstract:
Cephalexin is a very commonly prescribed orally administered antibiotic which has many potential side effects. Amongst these cholestatic jaundice has been infrequently reported as an adverse reaction. We present a case of a 57-year-old male who exhibited features of cholestatic jaundice including elevated liver function tests (LFTs) after taking cephalexin and showed improvement on removal of the offending agent. During this time he was symptomatically treated with cholestyramine. Complete resolution of LFTs was seen in four weeks. Cephalexin induced cholestasis is rare and hence requires a high degree of clinical suspicion for prompt diagnosis and treatment.
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