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Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Diabetes Mellitus: Overview and Type I Subtype01:22

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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
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Type I Diabetes III: Clinical Manifestations01:19

Type I Diabetes III: Clinical Manifestations

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Type 1 diabetes mellitus typically presents with rapid-onset symptoms due to the body’s inability to utilize glucose in the absence of insulin. Since insulin is required for glucose uptake into cells, its deficiency leads to hyperglycemia and cellular energy deprivation, resulting in characteristic clinical features.Polyuria and PolydipsiaOne of the earliest, most prominent symptoms is polyuria (excessive urination). When blood glucose concentrations rise above the renal threshold, the...
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Carbohydrate Metabolism01:36

Carbohydrate Metabolism

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Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
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Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Hypoglycemia01:26

Hypoglycemia

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Hypoglycemia is a blood glucose level below 70 mg/dL. It commonly occurs in individuals using insulin or insulin-secreting drugs, but may also arise in non-diabetic conditions. People with type 1 diabetes are at the highest risk because they depend on exogenous insulin. People with type 2 diabetes are also at risk, especially when treated with insulin or medications such as sulfonylureas, which increase insulin release regardless of blood glucose levels. It develops when insulin levels exceed...
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Updated: Apr 24, 2026

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT
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Diabetes in low-resourced countries.

Eran Ashwal1, Eran Hadar1, Moshe Hod1

  • 1Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Best Practice & Research. Clinical Obstetrics & Gynaecology
|September 4, 2014
PubMed
Summary
This summary is machine-generated.

Diabetes in pregnancy is a growing concern in developing nations due to lifestyle changes. Reliable data on maternal and newborn health impacts is scarce, necessitating better screening and management strategies.

Keywords:
developing worlddiabetesdiagnosisgestational diabeteslow-income countriesscreening

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Area of Science:

  • Global Health
  • Obstetrics and Gynecology
  • Endocrinology

Background:

  • Maternal and newborn health is a significant challenge in developing countries.
  • Low-income nations face demographic shifts and lifestyle changes, leading to increased prevalence of 'Western' diseases like diabetes.
  • There is a critical lack of reliable data on diabetes in pregnancy within these regions, impacting maternal and perinatal outcomes.

Purpose of the Study:

  • To present evidence on the magnitude and impact of diabetes in pregnancy in developing countries.
  • To discuss current interventions for screening and managing diabetes in pregnancy in these specific populations.

Main Methods:

  • This chapter synthesizes existing evidence and discusses interventions.
  • Focuses on data from low-income countries and specific patient populations.

Main Results:

  • Diabetes in pregnancy presents a substantial health challenge in developing nations.
  • Limited data exists on maternal and perinatal mortality and morbidity associated with diabetes in pregnancy in these settings.

Conclusions:

  • Urgent need for improved data collection on diabetes in pregnancy in developing countries.
  • Interventions for screening and management are crucial for improving maternal and newborn health outcomes.