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Updated: Apr 24, 2026
Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
New flavonoids from bioactive extract of Algerian medicinal plant Launeae arborescens
Khaled Sekkoum1, Nasser Belboukhari2, Abdelkrim Cheriti3
1Bioactive Molecule & Chiral separation Laboratory, University of Bechar, Bechar, 08000, Algeria.
Objective:
To investigate the butanol fraction of the water/acetone extract and isolate of the new flavonoids from Launeae arboescens.
Methods:
The compounds were isolated by liquid chromatographic methods and their structures were identified by using spectroscopic analysis.
Results:
THE ISOLATED COMPOUNDS WERE IDENTIFIED AS: 7-O-[α-rhamnopyranosyl 4',5,6-Trihydroxy flavone 1,4',5'-Di-Methoxy 7-(5″-Me Hexan)1-oyl flavanone 2, 3″-isopropyl pyrano [1″:7,4″:6] 3',4',5',5-Tetrahydroxy flavanone 3,5,4',5'-Tri-Hydroxy 7-(3″-Me butan) -yl flavanone 4, 5,7-Dihydroxy-2',4',5' -trimethoxy-isoflavanone 5,5,6,7,4'-tetrahydroxy flavonol 6,7-O-[α-rhamnopyranosyl-(1->6)-β-glucopyranosyl]- 4',5,7-tri-hydroxy-flavanone 7,7-O-[α-rhamnopyranosyl-(1->6)-β-glucopyranosyl] 3',5-Dihydroxy 4'-Methoxy flavanone 8.
Conclusions:
The presence of different types of bioactive flavonoids in Launeae arboescens extract can explain the large ethnopharmacological uses and the potential activity of this medicinal plant.
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