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Spermidinium closo-dodecaborate-encapsulating liposomes as efficient boron delivery vehicles for neutron capture
Shoji Tachikawa1, Tatsuro Miyoshi, Hayato Koganei
1Chemical Resources Laboratory, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan. hiro@res.titech.ac.jp.
Chemical Communications (Cambridge, England)
|September 4, 2014
Abstract:
closo-Dodecaborate-encapsulating liposomes were developed as boron delivery vehicles for neutron capture therapy. The use of spermidinium as a counter cation of closo-dodecaborates was essential not only for the preparation of high boron content liposome solutions but also for efficient boron delivery to tumors.
