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Updated: Apr 24, 2026

A Method for Lineage Tracing of Corneal Cells Using Multi-color Fluorescent Reporter Mice
Published on: December 18, 2015
Examining estrogen regulation of cancer stem cells through multicolor lineage tracing
Yongshu Zhang1, Gabriel Eades, Qun Zhou
1Department of Biochemistry and Molecular Biology, University of Maryland Baltimore School of Medicine, Biomedical Research Facility, 337, Baltimore, MD, 21210, USA.
Abstract:
We have designed a dual-color fluorescent reporter that can track microRNA expression in vitro, which can be used for lineage tracing experiments. We have used this system to track miR-140 promoter activity in breast cancer cells and to follow the impact of estrogen signaling in cancer stem cell subpopulations.
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