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[Relationship between genetic polymorphisms of matrix metalloproteinase-2 and -3 and susceptibility to silicosis]

Jie Kou1, Xueyun Fan1, Yaxin Shi1

  • 1School of Public Health, Hebei United University, Tangshan, Hebei Province 063000, China.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi = Zhonghua Laodong Weisheng Zhiyebing Zazhi = Chinese Journal of Industrial Hygiene and Occupational Diseases
|September 4, 2014
PubMed
Abstract

Insights

Genetic variations in matrix metalloproteinase-2 (MMP-2) are linked to silicosis risk. Specifically, carrying the T allele at the MMP-2 C-735T polymorphism increases susceptibility to this lung disease in dust-exposed workers.

Area of Science:

  • Environmental Health
  • Genetics
  • Occupational Medicine

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