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[Modular diet and parenteral support in persistent diarrhea]

F Barrera, M J Rebollo, J Espinoza

    Revista Chilena De Pediatria
    |May 1, 1989
    PubMed

    Insights

    Modular diets and parenteral nutrition aided infants with protracted diarrhea, improving hospitalization duration but showing persistent nutritional deficits. Recovery was noted post-discharge.

    Area of Science:

    • Pediatric Gastroenterology
    • Clinical Nutrition
    • Infectious Diseases

    Context:

    • Protracted diarrhea in infants presents significant nutritional challenges.
    • Nosocomial infections complicate recovery and prolong hospital stays.
    • Enteropathogenic E. coli and rotavirus are common etiological agents.

    Purpose:

    • To evaluate the efficacy of a modular diet combined with short-term parenteral nutrition in infants with protracted diarrhea.
    • To assess the nutritional impact and recovery patterns following this therapeutic approach.

    Summary:

    • Eleven infants with protracted diarrhea received modular diet and parenteral nutrition.
    • Studies included balance studies and peroral biopsies.
    • While hospitalization was shortened, a negative nutritional impact (decreased Weight/Age) persisted, with fecal lactic acid decreasing and disaccharidase activity remaining low.

    Impact:

    • Modular diets can reduce fecal volume and lactic acid excretion in infants with diarrhea.
    • Despite treatment, long-term nutritional deficits require attention.
    • Further research is needed to fully address the persistent nutritional impact.

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