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Updated: Apr 24, 2026

Investigating Receptor-ligand Systems of the Cellulosome with AFM-based Single-molecule Force Spectroscopy
Published on: December 20, 2013
Optical spectroscopy of molecular-rotor molecules adsorbed on cellulose
1Raymond and Beverly Sackler Faculty of Exact Sciences, School of Chemistry, Tel Aviv University , Tel Aviv 69978, Israel.
Abstract:
Steady-state and time-resolved emission techniques were used to study the fluorescence properties of two molecular rotors, thioflavin-T and auramine-O adsorbed on cellulose powder. Molecular rotors are known for their weak fluorescence intensity and short fluorescence lifetime when dissolved in liquids of low viscosity. We found that these molecular-rotor molecules when adsorbed on cellulose exhibit a rather strong steady-state fluorescence spectrum as well as long emission lifetime. We explain these results by the inhibition of segmental intramolecular rotation when these molecules are adsorbed on cellulose.
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