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Efficient and Consistent Generation of Retinal Pigment Epithelium/Choroid Flatmounts from Human Eyes for Histological Analysis
Published on: October 28, 2022
Reversibility of retinal pigment epithelium detachment parallel to acute intraocular pressure rise
Ya Xing Wang1, Jiang Ran, Li Hong Yang
1Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Ophthalmology and Visual Science Key Lab, Capital Medical University, Beijing, China.
Purpose:
To report on a reversibility of a retinal pigment epithelium (RPE) detachment in association with marked short-term changes in intraocular pressure (IOP).
Materials And Methods:
Three patients underwent a dark room provocative test for the diagnosis of angle-closure glaucoma. A spectral-domain optical coherent tomography of the macula was additionally performed.
Results:
On the macula optical coherent tomography images, all 3 patients showed an RPE detachment with decreased or completely disappeared after an IOP rise by 5 to 25 mm Hg, and which recurred after normalization of IOP.
Conclusion:
Slight detachments of the RPE may depend on acute IOP changes.

