Related Experiment Video
Updated: Apr 24, 2026

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
Published on: April 21, 2017
Strokes in children: a systematic review.
Lindsey Barst Gumer1, Michael Del Vecchio, Stephen Aronoff
1From the *Children's Hospital at Montefiore, New York, NY and †Department of Pediatrics, Temple University School of Medicine, Philadelphia, PA.
Pediatric strokes cause significant harm, and this systematic review identifies varied causes. A new diagnostic guide is presented for evaluating childhood stroke in emergency settings.
Area of Science:
- Neurology
- Pediatrics
- Systematic Review
Background:
- Pediatric strokes result in substantial morbidity and mortality.
- A systematic review is needed to guide the initial diagnostic approach for pediatric stroke.
Purpose of the Study:
- To review current data on the etiologies of stroke in children.
- To develop an initial diagnostic evaluation for pediatric stroke patients in the emergency department.
Main Methods:
- Systematic review conducted using PubMed and MEDLINE.
- Inclusion criteria focused on studies with extractable data on first strokes in pediatric patients.
- Data extraction included demographics and stroke etiologies.
Main Results:
- Twelve studies met the inclusion criteria.
- Data from 1455 children (21 days to 20 years) were analyzed.
- Etiologies of pediatric stroke were assessed.
Conclusions:
- Stroke etiologies in children are diverse and differ between ischemic and hemorrhagic types.
- A guide for the initial evaluation of pediatric stroke is provided based on this review.
Related Concept Videos
Stroke: Introduction and Types
Hemorrhagic Stroke ll: Pathophysiology
Hemorrhagic Stroke l: Introduction
Ischemic Stroke l: Introduction
Regulation of Stroke Volume
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Ischemic Stroke ll: Pathophysiology

