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Strokes in children: a systematic review

Lindsey Barst Gumer1, Michael Del Vecchio, Stephen Aronoff

  • 1From the *Children's Hospital at Montefiore, New York, NY and †Department of Pediatrics, Temple University School of Medicine, Philadelphia, PA.

Pediatric Emergency Care
|September 5, 2014
PubMed

Insights

Pediatric strokes cause significant harm, and this systematic review identifies varied causes. A new diagnostic guide is presented for evaluating childhood stroke in emergency settings.

Area of Science:

  • Neurology
  • Pediatrics
  • Systematic Review

Background:

  • Pediatric strokes result in substantial morbidity and mortality.
  • A systematic review is needed to guide the initial diagnostic approach for pediatric stroke.

Purpose of the Study:

  • To review current data on the etiologies of stroke in children.
  • To develop an initial diagnostic evaluation for pediatric stroke patients in the emergency department.

Main Methods:

  • Systematic review conducted using PubMed and MEDLINE.
  • Inclusion criteria focused on studies with extractable data on first strokes in pediatric patients.
  • Data extraction included demographics and stroke etiologies.

Main Results:

  • Twelve studies met the inclusion criteria.
  • Data from 1455 children (21 days to 20 years) were analyzed.
  • Etiologies of pediatric stroke were assessed.

Conclusions:

  • Stroke etiologies in children are diverse and differ between ischemic and hemorrhagic types.
  • A guide for the initial evaluation of pediatric stroke is provided based on this review.
Abstract

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