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In vivo studies of antibody dependent acantholysis
1Johns Hopkins University, Baltimore, Maryland.
Immunology Series
|January 1, 1989
Abstract:
The data that are being accumulated on the mechanisms by which pemphigus autoantibodies induce acantholysis in vivo conform that tissue injury in pemphigus is a complex phenomenon where several effector mechanisms may interact. Active research is being performed in many laboratories around the world, employing both in vitro and now in vivo models to further define this unique autoimmune disease.