[Relationship between IL-18 gene polymorphism and unexplained recurrent spontaneous abortion]

Dan Wang1, Chen Wang2, Ling-zhi Zheng2

  • 1Department of Reproduction, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China; Department of Obstetrics and Gynaecology, Taizhou Hospital of Zhejiang Province, Taizhou 317000, China.

Summary

Interleukin-18 (IL-18) gene polymorphisms, specifically rs187238, are linked to unexplained recurrent spontaneous abortion (URSA). The C allele significantly increases the risk of recurrent miscarriage.

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