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Related Concept Videos

Assessment of the Mouth01:26

Assessment of the Mouth

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A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
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Related Experiment Video

Updated: Apr 24, 2026

Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research
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Recurrent lip swelling: a diagnostic challenge.

Sonam Lakhani1, Sheena Barnett1, Anwar R Tappuni2

  • 1Respiratory Department, Homerton University Hospital, London, UK.

BMJ Case Reports
|September 5, 2014
PubMed
Summary
This summary is machine-generated.

Recurrent facial swelling, initially diagnosed as idiopathic angio-oedema, was found to be orofacial granulomatosis. This rare condition, presenting with lip swelling and gastrointestinal issues, requires specific diagnosis beyond standard allergy treatments.

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Area of Science:

  • Dermatology
  • Allergy and Immunology
  • Gastroenterology

Background:

  • A Caucasian woman in her late 20s presented with an 8-month history of recurrent facial angio-oedema.
  • Initial diagnosis was idiopathic angio-oedema, unresponsive to antihistamine treatment (40mg cetirizine/day).

Observation:

  • The patient reported no history of urticaria, airway symptoms, atopy, or family history of similar illness.
  • She also experienced intermittent gastrointestinal symptoms, including abdominal pain and diarrhea.
  • Routine investigations were unremarkable.

Findings:

  • Referral to dermatology led to a suspected diagnosis of orofacial granulomatosis.
  • Oral mucosa biopsy confirmed the diagnosis of this rare granulomatous disease.
  • Orofacial granulomatosis can be associated with Crohn's disease.

Implications:

  • Highlights the importance of considering orofacial granulomatosis in refractory angio-oedema cases.
  • Suggests a link between facial swelling, gastrointestinal symptoms, and granulomatous disease.
  • Emphasizes the need for a multidisciplinary approach in diagnosing rare conditions.