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Updated: Apr 24, 2026

Induction and Phenotyping of Acute Right Heart Failure in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension
Published on: March 17, 2022
Hypereosinophilic syndrome with large intracardiac thrombus
Kian-Guan Lee1, Matthew Bingfeng Chuah, Hak-Chiaw Tang
1Renal Medicine Department, Singapore General Hospital, Outram Road, Singapore 169608. kianguan.lee@mohh.com.sg.
Abstract:
As the nonspecific clinical presentation of hypereosinophilic syndrome (HES) may mimic many multisystemic diseases, it often presents as a diagnostic challenge. Herein, we report the case of a 60-year-old man who presented with progressive heart failure symptoms and eosinophilia. Despite extensive diagnostic evaluation, no underlying cause was found. Transthoracic echocardiography revealed a large left ventricular thrombus, which is suggestive of hypereosinophilic cardiac involvement. The patient was started on steroids and responded clinically and haematologically.
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