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Elevated resting heart rate is associated with dyslipidemia in middle-aged and elderly Chinese
Ji Chao Sun1, Xiao Lin Huang2, Xin Ru Deng2
1Key Laboratory for Endocrine and Metabolic Diseases, Ministry of Health, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, E-Institute of Shanghai Universities, Shanghai 200025, China; Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China; Laboratory of Endocrine and Metabolic Diseases, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, and Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
Insights
Elevated resting heart rate is linked to higher triglyceride and total cholesterol levels in middle-aged and older Chinese adults. This study highlights a potential cardiovascular risk factor in this population.
Area of Science:
- Cardiovascular Health
- Metabolic Syndrome
- Public Health Research
Background:
- Resting heart rate (RHR) is a simple physiological indicator.
- Blood lipid levels, including triglyceride (TG) and total cholesterol (TC), are key markers for cardiovascular disease risk.
- Understanding the relationship between RHR and blood lipids is crucial for preventive strategies.
Purpose of the Study:
- To investigate the association between RHR and blood lipid profiles.
- To determine if elevated RHR is a risk factor for dyslipidemia in Chinese adults.
Main Methods:
- A cross-sectional study included 9,415 Chinese subjects aged 40 years and above.
- RHR was measured, and serum levels of TG, TC, LDL-C, and HDL-C were analyzed.
- Dyslipidemia was defined based on the 2007 Chinese Guidelines.
Main Results:
- Subjects were categorized into four RHR groups: <70, 70-79, 80-89, and ≥90 beats/min.
- Higher RHR was significantly associated with elevated TG and TC levels (Ptrend <0.01).
- Individuals with RHR ≥90 beats/min had a 1.42-fold increased risk of high TG and a 1.33-fold increased risk of high TC compared to those with RHR <70 beats/min.
Conclusions:
- Elevated resting heart rate is significantly associated with higher triglyceride and total cholesterol levels.
- Higher RHR may serve as a predictive marker for dyslipidemia in middle-aged and elderly Chinese populations.
- These findings underscore the importance of monitoring RHR for cardiovascular risk assessment.
Objective:
To study the relationship between resting heart rate and blood lipid level.
Methods:
A total of 9 415 subjects aged ⋝ 40 years were included in the present study. Their resting heart rate was monitored and their serum levels of triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were measured to define dyslipidemia according to the 2007 Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults.
Results:
The subjects were divided into group A with their resting heart rate <70 beats/min, group B with their resting heart rate =70-79 beats/min, group C with their resting heart rate =80-89 beats/min, and group D with their resting heart rate ⋝ 90 beats/min. High TG, TC, and LDL-C were presented across the resting heart rate (Ptrend <0.01). Multiple logistic regression analysis revealed that the risk of high TG and TC was higher in subjects with their resting heart rate ⋝ 90 beats/min than in those with their resting heart rate <70 beats/min (OR=1.42; 95% CI: 1.16-1.74 and OR=1.33; 95% CI: 1.09-1.64, respectively).
Conclusion:
Elevated resting heart rate is associated with high TG and TC in middle-aged and elderly Chinese subjects.
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