Elevated resting heart rate is associated with dyslipidemia in middle-aged and elderly Chinese

Ji Chao Sun1, Xiao Lin Huang2, Xin Ru Deng2

  • 1Key Laboratory for Endocrine and Metabolic Diseases, Ministry of Health, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, E-Institute of Shanghai Universities, Shanghai 200025, China; Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China; Laboratory of Endocrine and Metabolic Diseases, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, and Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.

Insights

Elevated resting heart rate is linked to higher triglyceride and total cholesterol levels in middle-aged and older Chinese adults. This study highlights a potential cardiovascular risk factor in this population.

Area of Science:

  • Cardiovascular Health
  • Metabolic Syndrome
  • Public Health Research

Background:

  • Resting heart rate (RHR) is a simple physiological indicator.
  • Blood lipid levels, including triglyceride (TG) and total cholesterol (TC), are key markers for cardiovascular disease risk.
  • Understanding the relationship between RHR and blood lipids is crucial for preventive strategies.

Purpose of the Study:

  • To investigate the association between RHR and blood lipid profiles.
  • To determine if elevated RHR is a risk factor for dyslipidemia in Chinese adults.

Main Methods:

  • A cross-sectional study included 9,415 Chinese subjects aged 40 years and above.
  • RHR was measured, and serum levels of TG, TC, LDL-C, and HDL-C were analyzed.
  • Dyslipidemia was defined based on the 2007 Chinese Guidelines.

Main Results:

  • Subjects were categorized into four RHR groups: <70, 70-79, 80-89, and ≥90 beats/min.
  • Higher RHR was significantly associated with elevated TG and TC levels (Ptrend <0.01).
  • Individuals with RHR ≥90 beats/min had a 1.42-fold increased risk of high TG and a 1.33-fold increased risk of high TC compared to those with RHR <70 beats/min.

Conclusions:

  • Elevated resting heart rate is significantly associated with higher triglyceride and total cholesterol levels.
  • Higher RHR may serve as a predictive marker for dyslipidemia in middle-aged and elderly Chinese populations.
  • These findings underscore the importance of monitoring RHR for cardiovascular risk assessment.
Abstract

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