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[Prenatal factors associated with high BMI status of infants and toddlers]
Bingbing Guo1, Hong Mei1, Senbei Yang1
1Department of Woman and Child's Care and Adolescence Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Insights
Maternal passive smoking, parental obesity, and high birth weight are key factors for childhood high BMI. Prevention strategies should begin before pregnancy to address these risks effectively.
Area of Science:
- Pediatric Endocrinology
- Public Health
- Reproductive Health
Context:
- Childhood obesity is a growing global health concern.
- Early life factors significantly influence long-term health outcomes.
- Identifying prenatal risk factors is crucial for effective prevention.
Purpose:
- To investigate prenatal risk factors associated with high Body Mass Index (BMI) in children at one and two years of age.
- To determine the influence of maternal and paternal factors on infant and toddler BMI status.
Summary:
- A birth cohort study of 2,220 newborns followed for two years identified significant prenatal risk factors for high BMI.
- Maternal passive smoking during pregnancy, maternal pre-pregnancy overweight/obesity, paternal overweight/obesity, and high birth weight were associated with increased BMI in children.
- Prevalence of high BMI was 32.80% at one year and 26.23% at two years, with boys showing higher rates at age two.
Impact:
- Findings highlight the critical role of preconception and prenatal health in preventing childhood obesity.
- Intervention strategies should focus on parental weight management and smoking cessation before and during pregnancy.
- Early identification and management of high birth weight can contribute to obesity prevention efforts.
Objective:
To explore prenatal related factors of high BMI status in children at 1 and 2 years of age.
Method:
A total of 2 220 newborns from Shenyang, Wuhan and Guangzhou were recruited in this birth cohort, thereafter they were followed up to two years of age.Self-administered questionnaires were used to collect such variables as social-demographic characteristics and feeding practice, etc. The anthropometric measures of children were collected by trained health staff. The data were subjected to multiple logistic regression analysis to determine the related factors for high BMI among infants and toddlers.
Result:
The number of children with high BMI status were 550 (32.80%) at one year of age and 309 (26.23%) at two, respectively. The number of boys with high BMI status were 178 and girls 309 at age two years. The prevalence of high BMI status among boys (29.1%) at age two was significantly higher than that of girls (23.1%) (χ² = 5.52, P = 0.02). Logistic regression analysis showed that after the adjustment for sex, parental educational level, family economic status and other confounding factors, maternal passive smoking during pregnancy [OR:aged one:1.38 (1.05-1.82);aged two:1.48 (1.05-2.09)], maternal pre-pregnancy overweight and obesity [aged one:1.29 (1.05-1.58); aged two:1.35 (1.04-1.76)], paternal overweight and obesity [aged one:1.50 (1.21-1.87); aged two:1.47 (1.11-1.95)] and birth weight [aged one:1.53 (1.05-1.82); aged two:1.87 (1.33-2.63)]were identified to be associated with high BMI status in children.
Conclusion:
Maternal passive smoking during pregnancy, paternal and maternal (pre-pregnancy) overweight or obesity and high birth weight are found to be important related factors for high BMI status in young children. Childhood overweight/obesity prevention should be considered starting as early as before pregnancy.
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