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The economics of medicines optimization: policy developments, remaining challenges and research priorities
Rita Faria1, Marco Barbieri2, Kate Light3
1Centre for Health Economics, University of York, York, UK rita.nevesdefaria@york.ac.uk.
Background:
This review scopes the evidence on the effectiveness and cost-effectiveness of interventions to improve suboptimal use of medicines in order to determine the evidence gaps and help inform research priorities.
Sources Of Data:
Systematic searches of the National Health Service (NHS) Economic Evaluation Database, the Cochrane Database of Systematic Reviews and the Database of Abstracts of Reviews of Effects.
Areas Of Agreement:
The majority of the studies evaluated interventions to improve adherence, inappropriate prescribing and prescribing errors.
Areas Of Controversy:
Interventions tend to be specific to a particular stage of the pathway and/or to a particular disease and have mostly been evaluated for their effect on intermediate or process outcomes.
Growing Points:
Medicines optimization offers an opportunity to improve health outcomes and efficiency of healthcare.
Areas Timely For Developing Research:
The available evidence is insufficient to assess the effectiveness and cost-effectiveness of interventions to address suboptimal medicine use in the UK NHS. Decision modelling, evidence synthesis and elicitation have the potential to address the evidence gaps and help prioritize research.
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