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Updated: Apr 24, 2026

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Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
Published on: January 12, 2017
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Direct pulp capping in an immature incisor using a new bioactive material.
Sham S Bhat1, Sundeep K Hegde1, Fardin Adhikari1
1Department of Paedodontics and Preventive Dentistry, Yenepoya Dental College, Mangalore, Karnataka, India.
Contemporary Clinical Dentistry
|September 6, 2014
Summary
This study highlights Biodentine
Area of Science:
- Dentistry
- Regenerative Dentistry
- Pediatric Dentistry
Background:
- Traumatized immature incisors require pulp preservation for apexogenesis.
- Effective pulpal protection and marginal seal are crucial to prevent microleakage.
Observation:
- An 8-year-old female with an Ellis Class 3 fracture of an immature incisor underwent a partial pulpotomy.
- The pulp was sealed with Biodentine, a bioactive material, and the fractured segment was reattached.
Findings:
- Follow-up at 1, 3, 6, and 12 months showed continued apical closure and maintained pulp vitality.
- The patient remained asymptomatic throughout the observation period.
Implications:
- Biodentine shows potential as an effective pulp capping material for traumatized immature teeth.
- This approach can stimulate apexogenesis, dentine replacement, and pulp protection, aiding in natural tooth repair.

