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Thoracic Imaging Findings of Collagen Vascular Diseases: A CT Study

Mehrdad Bakhshayesh Karam1, Hamideh Peivareh1, Leila Mosadegh2

  • 1Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Tanaffos
|September 6, 2014
PubMed

Insights

Collagen vascular diseases (CVDs) commonly affect the lungs. Thoracic CT scans reveal reticulation, septal thickening, and ground glass opacity, with obliterative bronchiolitis being a frequent finding.

Area of Science:

  • Radiology
  • Pulmonary Medicine
  • Rheumatology

Background:

  • Collagen vascular diseases (CVDs) are recognized causes of significant pulmonary morbidity.
  • Thoracic computed tomography (CT) plays a crucial role in diagnosing lung involvement in CVDs.

Purpose of the Study:

  • To identify and characterize thoracic CT findings in patients with collagen vascular diseases.
  • To correlate CT patterns with histopathological findings in CVDs.

Main Methods:

  • Retrospective analysis of 56 patients with histopathologically and clinically proven CVDs.
  • Evaluation of CT findings including presence, extent, and distribution by a radiologist.

Main Results:

  • Lung parenchyma involvement was observed in 96.4% of patients, predominantly in lower lobes (89.2%).
  • Common CT patterns included reticulation (55.3%), peripheral subpleural interlobular septal thickening (51.7%), and ground glass opacity (50%).
  • Obliterative bronchiolitis (44.6%) and non-specific interstitial pneumonia (33.9%) were the most frequent histopathological findings.

Conclusions:

  • A combination of reticular pattern, septal thickening, and ground glass opacity is characteristic of CVDs.
  • Obliterative bronchiolitis appears more prevalent in CVDs than previously reported.
  • CT patterns of pulmonary fibrosis in CVDs align with findings in other studies.
Abstract

Keywords:
Collagen vascular diseaseImagingThorax

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