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Updated: Apr 24, 2026

Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging
Published on: May 24, 2021
Current clinical applications of cardiovascular magnetic resonance imaging
L Scholtz1, A Sarkin2, Z Lockhat3
1Department of Radiology, Steve Biko Hospital, Pretoria, South Africa. leonie@scholtzrad.co.za.
Insights
Cardiovascular magnetic resonance (CMR) imaging offers detailed myocardial assessment. This versatile technique aids in diagnosing heart conditions like ischaemic heart disease and cardiomyopathies, benefiting African patients with proper training.
Area of Science:
- Cardiovascular Imaging
- Cardiac Magnetic Resonance
Background:
- Cardiovascular magnetic resonance (CMR) imaging excels in assessing myocardial anatomy, function, and mass.
- Ischaemic heart disease diagnosis increasingly utilizes myocardial perfusion and late enhancement imaging.
- Late enhancement patterns are crucial for diagnosing various cardiomyopathies, myocarditis, and cardiac tumors.
Purpose of the Study:
- To highlight the diagnostic capabilities of cardiovascular magnetic resonance (CMR) imaging.
- To emphasize the potential benefits of CMR for patients with a high incidence of cardiovascular disease in Africa.
- To underscore the importance of training and collaboration for optimal CMR utilization.
Main Methods:
- Evaluation of myocardial anatomy, function, and mass using CMR.
- Assessment of myocardial perfusion (pre- and post-stress).
- Analysis of late enhancement patterns for disease detection.
Main Results:
- CMR is unsurpassed for detailed myocardial evaluation.
- Late enhancement patterns significantly aid in diagnosing conditions like myocarditis, cardiomyopathies, and infiltrative diseases.
- Myocardial perfusion imaging is vital for assessing myocardial viability in ischaemic heart disease.
Conclusions:
- Cardiovascular magnetic resonance (CMR) is a versatile and evolving technique for diagnosing diverse cardiac conditions.
- Proper utilization of CMR, supported by training and interdisciplinary cooperation, can greatly benefit African patients.
- The technique's ability to assess anatomy, function, perfusion, and tissue characterization makes it invaluable.
Abstract:
Cardiovascular magnetic resonance (CMR) imaging is unsurpassed in the evaluation of myocardial anatomy, function and mass. Myocardial perfusion pre- and post-stress, as well as late enhancement is increasingly used in the work-up for ischaemic heart disease, especially in establishing the presence of myocardial viability. Late enhancement patterns can contribute substantially to the diagnosis of myocarditis and various cardiomyopathies as well as infiltrative diseases and tumours. With their high incidence of cardiovascular disease, patients on the African continent could potentially benefit enormously from the proper utilisation of this exciting, continually evolving and versatile technique, via thorough didactic and clinical training as well as interdisciplinary co-operation.
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