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Self-limiting corneal edema with multiple parallel lines on the endothelium (SCEMPLE)
Sofie Le Piane1, Toine Hillenaar, Lies Remeijer
1Department of Ophthalmology, University Hospitals Leuven, Louvain, Belgium.
International Ophthalmology
|September 7, 2014
Summary
Self-limiting corneal edema with parallel lines (SCEMPLE) resolves spontaneously within a week. In vivo confocal microscopy revealed characteristic endothelial changes, suggesting an etiology distinct from endotheliitis.
Area of Science:
- Ophthalmology
- Corneal Diseases
- Microscopy
Background:
- Unilateral self-limiting corneal edema and multiple parallel lines on the endothelium (SCEMPLE) is a rare condition.
- Understanding its natural course and diagnostic features is crucial for appropriate management.
Observation:
- Five patients with SCEMPLE presented with blurred vision.
- Slit-lamp examination and white-light in vivo confocal microscopy (IVCM) were utilized.
- IVCM visualized hyperreflective material between endothelial cells, with spot-like holes and precipitates.
Findings:
- SCEMPLE demonstrated characteristic IVCM findings, distinct from endotheliitis.
- The condition resolved spontaneously within one week in all cases.
- A decrease in endothelial cell density was the only noted sequela.
Implications:
- SCEMPLE is a self-limiting condition requiring no specific treatment.
- IVCM findings support a unique etiology separate from endotheliitis.
- Endothelial cell loss is a potential long-term consequence requiring monitoring.
