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Published on: January 26, 2024
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Short-term hearing results using ossicular replacement prostheses of hydroxyapatite versus titanium
Jong-Ik Lee1, Shin-Hyuk Yoo, Chang Wook Lee
1Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, 86 Asanbyeongwon-gil, Songpa-gu, Seoul, 138-736, Korea.
Summary
Hydroxyapatite (HA) and titanium (Ti) prostheses for ossicular replacement surgery showed similar short-term hearing results. Both materials, partial or total ossicular replacement prostheses (PORP or TORP), effectively reduced air-bone gaps, indicating good functional outcomes.
Area of Science:
- Otolaryngology
- Audiology
- Biomaterials Science
Background:
- Chronic otitis media with or without cholesteatoma often necessitates ossiculoplasty.
- Partial or total ossicular replacement prostheses (PORP or TORP) are used to reconstruct the ossicular chain.
- The choice of biomaterial, such as hydroxyapatite (HA) or titanium (Ti), may influence surgical outcomes.
Purpose of the Study:
- To compare the short-term audiologic outcomes of ossiculoplasty using HA versus Ti prostheses.
- To evaluate the effectiveness of PORP and TORP made from these materials.
Main Methods:
- Fifty-two patients undergoing ossiculoplasty were enrolled.
- Audiologic results were assessed at 6 months postoperatively.
- Preoperative and postoperative air-conduction and bone-conduction thresholds were measured; success defined as a postoperative air-bone gap (ABG) < 20 dB.
Main Results:
- All prosthesis types significantly decreased postoperative ABGs.
- Titanium PORP showed a non-significantly higher success rate (89%) than HA PORP (72%).
- Hydroxyapatite TORP demonstrated a non-significantly higher success rate (100%) than Ti TORP (67%); no significant differences in ABGs between HA and Ti groups at any frequency.
Conclusions:
- Both hydroxyapatite and titanium prostheses yield good short-term functional results in ossiculoplasty.
- Material choice between HA and Ti appears to be based on surgeon preference and cost-effectiveness.
- Further long-term randomized controlled trials with larger sample sizes are required to definitively establish differences.

