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[Giovanni Martinotti and experimental pancreatectomy, a century ago]
B Bruni1, P L Barbero, A Blatto
1Centro di Diabetologia Karen Bruni Böcher, Museo del Diabete, Torino.
Abstract:
On July 13th, 1888, Giovanni Martinotti (1857-1928) announced in Torino the feasibility of a total pancreatectomy in the dog. The essential details for a successful outcome of the operation, as described by Martinotti, were employed by Oscar Minkowski (1859-1931) in Strassburg for the demonstration of diabetes after total removal of pancreas in the dog, on May 22nd, 1889. Martinotti's work deserves a reevaluation in the history of diabetology.