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Impact of cardiovascular counseling and screening in Hodgkin lymphoma survivors

Laurien A Daniëls1, Stijn D G Krol1, Michiel A de Graaf2

  • 1Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands.

International Journal of Radiation Oncology, Biology, Physics
|September 9, 2014
PubMed

Insights

Cardiovascular disease screening in Hodgkin lymphoma survivors is well-received, improving patient understanding of risks and benefits. Counseling enhances satisfaction, outweighing any emotional burden from screening.

Area of Science:

  • Cardiology
  • Oncology
  • Health Outcomes Research

Background:

  • Cardiovascular disease (CVD) is a leading cause of non-cancer death in Hodgkin lymphoma (HL) survivors, particularly those treated with mediastinal irradiation.
  • The benefits and burdens of CVD screening in this population remain unclear, with potential impacts on health-related quality of life (HRQL).

Purpose of the Study:

  • To evaluate the HRQL, emotional and practical burden, and perceived benefits of CVD screening using computed tomography angiography (CTA) in HL survivors.
  • To assess the effect of CVD-specific counseling on patient satisfaction and information provision.

Main Methods:

  • A phase 2 screening study involving HL survivors who underwent CTA.
  • HRQL was assessed using the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Core Questionnaire C30.
  • Information provision and satisfaction were evaluated using the EORTC INFO-25 questionnaire, with assessments at baseline and post-screening.

Main Results:

  • Most participants (93%) were content with screening, and 80% found the focus on late effects not burdensome.
  • Screening had a minor impact on social functioning and global quality of life.
  • Significant improvements in perceived information about disease, tests, and treatment were observed post-screening (P<.01).

Conclusions:

  • CVD screening via CTA was viewed favorably by HL survivors, irrespective of detected abnormalities.
  • Extensive counseling significantly enhanced information provision and satisfaction.
  • The perceived benefits of screening and subsequent cardiac intervention outweighed the emotional and practical burdens.
Abstract

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