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Published on: February 28, 2019
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Olfactory neuroblastoma and olfactory ventricle. A case report
Eugenio Pozzati1, Matteo Martinoni2, Gianluca Marucci3
1Department of Neurosurgery, IRCCS Neurological Research Hospital; Bologna, Italy - eugenio.pozzati@ausl.bo.it.
The Neuroradiology Journal
|September 9, 2014
Summary
A rare case of olfactory neuroblastoma (ONB) spreading through a newly identified "olfactory ventricle" is presented. This anatomical variant may influence tumor growth and diffusion patterns.
Area of Science:
- Neuro-oncology
- Neuroanatomy
- Surgical pathology
Background:
- Olfactory neuroblastoma (ONB) is a rare malignant tumor arising from the olfactory epithelium.
- Understanding the pathways of ONB spread is crucial for effective treatment and prognosis.
Observation:
- A case involving a dumbbell-shaped olfactory neuroblastoma with both nasal and intracerebral components is described.
- A previously unrecognized anatomical variant, termed the "olfactory ventricle," was identified within the olfactory bulb and nerve during surgical exploration.
Findings:
- The "olfactory ventricle" is a hollow cavity within the olfactory bulb and nerve.
- This cavity may potentially connect to the subventricular zone of the frontal horn of the lateral ventricle.
- This anatomical variation may serve as a pathway for tumor seeding and dissemination of olfactory neuroblastoma.
Implications:
- The discovery of the "olfactory ventricle" necessitates closer examination of this structure in cases of olfactory neuroblastoma.
- Recognizing this pathway could improve surgical planning and understanding of ONB's intracerebral spread.
- Further research into the "olfactory ventricle" is warranted to elucidate its role in neuro-oncology.
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