Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Diabetic Retinopathy

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

Anatomy of the Eyeball

Anatomy of the Eyeball

The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Niveau (Level) as a Key Predictor of the Absence of Macular Hole in Subinternal Limiting Membrane Hemorrhage Secondary to Retinal Arterial Macroaneurysm Rupture.

Ophthalmology. Retina·2026

Same author

Comparative flow and operating efficiency of TDC Veloce 27-gauge vitrectome.

Retina (Philadelphia, Pa.)·2026

Same author

Caffeine Therapy Reduces Severe Retinopathy of Prematurity in Neonates with Gestational Age between 23 and 28 Weeks.

Ophthalmology science·2025

Same author

Efficacy, durability, and safety of faricimab with extended dosing up to every 16 weeks in diabetic macular edema: 2-year results from the Japan subgroup of the phase 3 YOSEMITE trial.

Japanese journal of ophthalmology·2024

Same author

Efficacy, durability, and safety of faricimab with extended dosing up to every 16 weeks in Japanese patients with diabetic macular edema: 1-year results from the Japan subgroup of the phase 3 YOSEMITE trial.

Japanese journal of ophthalmology·2023

Same author

Displacement of submacular hemorrhage secondary to age-related macular degeneration with subretinal injection of air and tissue plasminogen activator.

Scientific reports·2022

Search research articles

Related Experiment Video

Updated: Apr 24, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Idiopathic macular hole.

¹Hyogo Prefectural Amagasaki Hospital, Amagasaki, Hyogo, Japan.

Developments in Ophthalmology

|September 9, 2014

Summary

Idiopathic macular hole surgery, using microincision vitrectomy, effectively treats vitreomacular adhesion. Post-surgery optical coherence tomography (OCT) confirms visual improvements and aids understanding of the healing process.

Area of Science:

Ophthalmology
Surgical Innovation

Background:

Idiopathic macular hole results from vitreomacular interface adhesion.
Vitrectomy surgery is a primary treatment option.

Purpose of the Study:

To describe the pathology and surgical treatment of idiopathic macular holes.
To highlight advances in minimally invasive macular hole surgery.

Main Methods:

Vitrectomy with internal limiting membrane (ILM) peeling.
Fluid-air exchange and gas tamponade.
Optical coherence tomography (OCT) for presurgical evaluation and postsurgical monitoring.

Main Results:

Microincision vitrectomy surgery (MIVS) offers minimal invasiveness.
Significant visual improvement is a common outcome.

More Related Videos

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

Published on: September 11, 2013

Related Experiment Videos

Last Updated: Apr 24, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

Published on: September 11, 2013

Postsurgical OCT imaging correlates with subjective visual improvement.

Conclusions:

Vitrectomy is an effective treatment for idiopathic macular holes.
Advances like inverted ILM peeling and 27-gauge vitrectomy enhance surgical outcomes and minimize invasiveness.