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Eosinophilic gastroenteritis: a case series from iran.
Mohammad Bagheri1, Mandana Ashrafi2, Mehdi Mohamadnejad1
1Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran ; Sasan Alborz Biomedical Research, Institute, Tehran, Iran.
Middle East Journal of Digestive Diseases
|September 9, 2014
Summary
Eosinophilic gastroenteritis (EG) in Iran presents similarly to other regions, with most patients responding to oral corticosteroids. Close follow-up is crucial for managing relapses in this rare GI disorder.
Area of Science:
- Gastroenterology
- Immunology
- Internal Medicine
Background:
- Eosinophilic gastroenteritis (EG) is a rare gastrointestinal inflammatory disorder.
- Previous case series are primarily from Western countries and East Asia.
- No reports on EG patients from the Middle East region exist.
Purpose of the Study:
- To describe the clinical characteristics of EG patients in Iran.
- To evaluate treatment response and relapse rates in Iranian EG patients.
Main Methods:
- Retrospective review of 22 EG patient charts from 1997-2010.
- Evaluation of clinical features, treatment outcomes, and relapse rates.
- Median follow-up duration of 36.5 months.
Main Results:
- 22 patients (mean age 45.1 years) diagnosed with EG.
- 90% had mucosal involvement; 20 patients responded well to oral corticosteroids.
- Relapse rate was 33%, managed with corticosteroids; two patients required azathioprine.
Conclusions:
- Clinical characteristics and treatment responses in Iranian EG patients align with global reports.
- Close post-treatment follow-up is essential for early detection of relapses.
