Related Experiment Video
Updated: Apr 24, 2026
Teratoma Generation in the Testis Capsule
Published on: November 7, 2011
Growing teratoma syndrome
Anna Scavuzzo1, Zael Arturo Santana Ríos1, Nancy Reynoso Noverón1
1Department of Urology, Instituto Nacional de Cancerología (INCan), Avenida San Fernando 22, Colonia Seccion XVI, Tlalpan, 14080 Mexico City, DF, Mexico.
Abstract:
Growing teratoma syndrome (GTS) is a rare clinical entity, which presents with enlarging teratomas masses of the retroperitoneum or other locations, occurring during or after systemic chemotherapy for the treatment of nonseminomatous germ cell of the testis (NSGCT), with normalised tumour markers. Awareness of this syndrome is necessary in order to prevent unnecessary chemotherapy and allow optimal management. Prognosis is excellent after the excision of these tumors, but surgery has to be as complete as possible. Surgical resection of bulky GTS lesions is technically challenging; intraoperative complications may occur; that is, why the treatment must not be delayed. Our experience in the surgical management of these lesions is reviewed in the following work.
Related Concept Videos
01:07Teratogenicity
02:23Abnormal Proliferation
02:07Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
02:30Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...