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Related Experiment Video

Updated: Apr 24, 2026

Teratoma Generation in the Testis Capsule
05:24

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Published on: November 7, 2011

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Growing teratoma syndrome.

Anna Scavuzzo1, Zael Arturo Santana Ríos1, Nancy Reynoso Noverón1

  • 1Department of Urology, Instituto Nacional de Cancerología (INCan), Avenida San Fernando 22, Colonia Seccion XVI, Tlalpan, 14080 Mexico City, DF, Mexico.

Case Reports in Urology
|September 9, 2014
PubMed
Summary

Growing teratoma syndrome (GTS) is a rare condition following testicular cancer chemotherapy. Early surgical removal of enlarging teratomas is crucial for excellent outcomes, despite potential surgical challenges.

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Germ Cell Tumors

Background:

  • Growing teratoma syndrome (GTS) is a rare entity characterized by enlarging teratomas in the retroperitoneum or other sites.
  • It occurs during or after chemotherapy for nonseminomatous germ cell tumors of the testis (NSGCT), despite normalized tumor markers.

Purpose of the Study:

  • To highlight the importance of recognizing GTS to avoid unnecessary chemotherapy.
  • To emphasize the necessity of prompt and complete surgical resection for optimal patient outcomes.

Main Methods:

  • Review of surgical management experience with bulky Growing Teratoma Syndrome lesions.
  • Analysis of intraoperative challenges and complications associated with surgical resection.

Main Results:

  • Prognosis is excellent following complete surgical excision of GTS tumors.
  • Surgical resection of bulky lesions can be technically challenging, necessitating careful planning and execution.

Conclusions:

  • Awareness of GTS is critical for appropriate clinical management.
  • Timely and complete surgical intervention is the cornerstone of successful treatment for Growing Teratoma Syndrome.