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Corrected QT-interval and dispersion after revascularization by percutaneous coronary intervention and coronary

Fardin Mirbolouk1, Samira Arami, Arsalan Salari

  • 1Guilan University of Medical Sciences, Rasht, Iran. samira_523@yahoo.com.

The Journal of Invasive Cardiology
|September 9, 2014
PubMed

Insights

Percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) both improve QT parameters in chronic ischemia. QT dispersion significantly decreases after both procedures, while QT interval shows varied initial changes post-CABG before improving.

Area of Science:

  • Cardiology
  • Cardiac Electrophysiology
  • Interventional Cardiology

Background:

  • Electrocardiography (ECG) parameters, including QT interval (QTI) and QT dispersion (QTd), are crucial for predicting cardiac events in ischemic heart disease.
  • Prolonged QTI and QTd are associated with poor prognosis and increased risk of fatal arrhythmias.
  • Revascularization procedures like PCI and CABG aim to improve cardiac perfusion, potentially impacting these ECG markers.

Purpose of the Study:

  • To compare the effects of percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) on QT interval and QT dispersion in patients with chronic ischemia.
  • To assess changes in corrected QT interval (QTc) and corrected QT dispersion (QTcd) following these revascularization strategies.

Main Methods:

  • A prospective study involving 141 patients with coronary artery disease (70 PCI, 71 CABG).
  • Standard 12-lead ECGs were recorded pre-procedure, immediately post-procedure, 24 hours, and 7 days post-procedure.
  • Corrected QT interval (QTc) and corrected QT dispersion (QTcd) were measured and compared between the PCI and CABG groups.

Main Results:

  • Both PCI and CABG led to a significant reduction in QT dispersion (QTcd) by 7 days post-procedure.
  • PCI resulted in a consistent decrease in corrected QT interval (QTc) after 7 days.
  • Following CABG, QTc initially increased but subsequently decreased within 7 days, showing a different temporal pattern compared to PCI.

Conclusions:

  • Revascularization through either PCI or CABG can effectively improve QT interval and QT dispersion parameters in patients with chronic ischemia.
  • Both procedures demonstrate a positive impact on ventricular electrical homogeneity and stability, as indicated by QT parameter changes.
Abstract

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