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Micronutrients and dengue.

Sundus Ahmed1, Julia L Finkelstein1, Anna M Stewart1

  • 1Division of Nutritional Sciences, Cornell University, Ithaca, New York; Center for Global Health and Translational Science, State University of New York Upstate Medical University, Syracuse, New York; Division of Infectious Diseases, St. John's Research Institute, Bangalore, India; Escuela Superior Politécnica del Litoral, Guayaquil, Ecuador.

The American Journal of Tropical Medicine and Hygiene
|September 10, 2014
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Summary
This summary is machine-generated.

Micronutrient roles in dengue virus infection require more research. While vitamins D and E show promise, current evidence is limited, necessitating larger, well-designed studies for dengue treatment and prevention strategies.

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Area of Science:

  • Virology
  • Nutritional Science
  • Public Health

Background:

  • Dengue virus infection is a significant global health concern, transmitted by mosquitoes.
  • Effective treatments and vaccines are lacking, highlighting the need to investigate host factors like nutrition.
  • Nutrition's impact on infectious disease progression is well-documented, offering potential low-cost interventions.

Purpose of the Study:

  • To review existing evidence on the role of micronutrients in dengue virus infection.
  • To identify knowledge gaps and inconsistencies in current research.
  • To explore potential nutritional strategies for managing dengue.

Main Methods:

  • Systematic review of literature on micronutrients and dengue virus.
  • Analysis of study findings regarding nutritional status and disease progression.
  • Identification of promising micronutrients based on available trial data.

Main Results:

  • Significant issues and inconsistent results were found across studies.
  • Limited literature restricts the ability to make definitive recommendations.
  • Vitamins D and E demonstrated potential benefits in preliminary supplementation trials.

Conclusions:

  • The role of micronutrients in dengue virus infection is an emerging and important research area.
  • Further investigation is crucial to understand how micronutrients affect dengue.
  • Well-designed studies with larger sample sizes are needed to establish evidence-based recommendations.