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Can early skin care normalise dry skin and possibly prevent atopic eczema? A pilot study in young infants
B K Kvenshagen1, K-H Carlsen2, P Mowinckel3
1Department of Paediatrics, Oestfold Hospital Trust, Fredrikstad, Norway.
Insights
Frequent oil baths for infants with dry skin significantly reduced xerosis and may help prevent atopic eczema (AE). Early intervention with regular oil baths shows promising results for infant skin health.
Area of Science:
- Dermatology
- Pediatrics
- Preventive Medicine
Background:
- Atopic eczema (AE) affects 20% of children in Northern countries, often starting in infancy.
- Infant AE is linked to a compromised skin barrier, increased water loss, and lipid layer defects.
- Emollients and oil baths are used to restore the skin barrier, but their preventive role for xerosis and AE is unclear.
Purpose of the Study:
- To assess if early, frequent use of oil baths and facial fat cream can reduce xerosis and potentially prevent atopic eczema in infants.
- To evaluate the impact of intensive infant skincare on skin quality at six months of age.
Main Methods:
- A controlled pilot study involved 56 six-week-old infants diagnosed with xerosis but without AE.
- One clinic provided intervention (frequent oil baths/facial cream), while five clinics served as observation controls.
- Skin quality was scored (0-4) at baseline, three, and six months, with six-month scores as the primary outcome.
Main Results:
- Infants receiving frequent oil baths showed significantly more normal skin (75%) at six months compared to the observation group (37.5%) (p<0.001).
- The intervention group had a lower incidence of probable atopic eczema (4.0% vs. 19.0%).
- Regular oil baths (2-7 times/week) were well-tolerated, with no reported adverse reactions.
Conclusions:
- Regular infant oil baths appear effective in reducing xerosis.
- Frequent use of oil baths may offer a preventive strategy for atopic eczema in infants.
- Early and consistent application of oil baths is a safe and potentially beneficial skincare practice for infants with dry skin.
Background:
Atopic eczema (AE) affects approximately 20% of children in Northern countries. Onset during early infancy is common and is characterised by altered skin barrier, increased water loss and defective lipid layer. Restoration of skin barrier by emollients and/or oil baths is an important part of AE treatment, but its role in preventing xerosis and AE is unknown. The present pilot study aimed to assess if xerosis, and possibly AE, could be reduced at six months of age by early introduction of frequent oil baths/facial fat cream in infants with dry skin.
Methods:
A controlled intervention pilot study included 56 six-week-old infants with xerosis, but not AE. Skin quality score ranging from 0 (normal skin) to 4 (probable AE), was assessed at inclusion, three and six months of age, with skin quality at six months as main outcome. One well baby clinic was recruited for intervention, frequent skin care (oil bath (0.5 dl) and facial fat cream, five well baby clinics recruited for observation only.
Results:
The intervention group (n=24) had more often normal skin (75%) at six months than the observation group (37.5%) (p<0.001), and less often probable AE (4.0 vs. 19.0%, respectively, ns). Oil baths were performed regularly, 2-4 up to 5-7 times/week in the intervention group, vs. fewer oil baths with sparse volume of oil in the observation group. No adverse reactions were reported.
Conclusion:
Regular oil baths in infants seem to reduce xerosis and may possibly reduce atopic eczema.
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