Can early skin care normalise dry skin and possibly prevent atopic eczema? A pilot study in young infants

B K Kvenshagen1, K-H Carlsen2, P Mowinckel3

  • 1Department of Paediatrics, Oestfold Hospital Trust, Fredrikstad, Norway.

Insights

Frequent oil baths for infants with dry skin significantly reduced xerosis and may help prevent atopic eczema (AE). Early intervention with regular oil baths shows promising results for infant skin health.

Area of Science:

  • Dermatology
  • Pediatrics
  • Preventive Medicine

Background:

  • Atopic eczema (AE) affects 20% of children in Northern countries, often starting in infancy.
  • Infant AE is linked to a compromised skin barrier, increased water loss, and lipid layer defects.
  • Emollients and oil baths are used to restore the skin barrier, but their preventive role for xerosis and AE is unclear.

Purpose of the Study:

  • To assess if early, frequent use of oil baths and facial fat cream can reduce xerosis and potentially prevent atopic eczema in infants.
  • To evaluate the impact of intensive infant skincare on skin quality at six months of age.

Main Methods:

  • A controlled pilot study involved 56 six-week-old infants diagnosed with xerosis but without AE.
  • One clinic provided intervention (frequent oil baths/facial cream), while five clinics served as observation controls.
  • Skin quality was scored (0-4) at baseline, three, and six months, with six-month scores as the primary outcome.

Main Results:

  • Infants receiving frequent oil baths showed significantly more normal skin (75%) at six months compared to the observation group (37.5%) (p<0.001).
  • The intervention group had a lower incidence of probable atopic eczema (4.0% vs. 19.0%).
  • Regular oil baths (2-7 times/week) were well-tolerated, with no reported adverse reactions.

Conclusions:

  • Regular infant oil baths appear effective in reducing xerosis.
  • Frequent use of oil baths may offer a preventive strategy for atopic eczema in infants.
  • Early and consistent application of oil baths is a safe and potentially beneficial skincare practice for infants with dry skin.
Abstract

Related Concept Videos

Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
81
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
3.3K
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
2.4K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.1K
Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
7.9K
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.4K