Surgical considerations for removal of giant tumor of the right adrenal
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Updated: Apr 24, 2026

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach
Published on: August 8, 2025
Giuseppe Pedullà1, Paolo Sapienza2, Annalisa Paliotta2
1Pietro Valdoni Department of Surgery, Sapienza University of Rome, Rome, Italy giuseppe.pedulla@uniroma1.it.
Background/Aim:
Complete surgical removal is the only potentially curative approach for adrenal tumors. Our series of patients affected with giant right adrenal tumors, as well as the open surgical modalities used to obtain a complete tumor resection with safe vascular control were analyzed.
Materials And Methods:
Nine patients (mean age=57 years) affected with a giant right adrenal tumor who underwent open surgical removal of the mass form the basis of the present analysis. A midline incision was performed. Large mobilization of the liver was performed to obtain good and safe exposure of the vascular pedicles.
Results:
An en bloc R0 tumor resection was accomplished in all cases. Histology revealed an adrenal cortical carcinoma in all patients. No local recurrence was noted at a mean follow-up of 14 months.
Conclusion:
Radical surgery is the only curative approach and is recommended for all patients, whenever technically feasible, through open access in cases of giant right adrenal carcinoma.

