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What we talk about when we talk about the default mode network.

Felicity Callard1, Daniel S Margulies2

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Frontiers in Human Neuroscience
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PubMed
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The default mode network (DMN) is a brain network active during rest. Understanding its role in thought and brain dynamics is a key challenge in neuroscience.

Keywords:
fMRIfunctional connectivityhistory of cognitive neurosciencemind wanderingneuroanatomyresting state

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Area of Science:

  • Neuroscience
  • Cognitive Neuroscience

Background:

  • The default mode network (DMN) is defined by brain regions active during resting states.
  • It emerged as a significant research focus in the early 21st century.

Purpose of the Study:

  • To critically reflect on the origin, function, and future of the DMN.
  • To examine controversies and interdisciplinary research enabled by the DMN.

Main Methods:

  • Review of scientific literature and conceptual analysis.
  • Discussion of empirical and theoretical neuroscientific investigations.

Main Results:

  • The DMN's emergence resulted from converging research.
  • Controversies exist regarding its definition, function, and localization.

Conclusions:

  • The DMN has facilitated current understanding of brain dynamics and thought.
  • Future research may explore mechanisms of thought beyond the DMN's centrality.