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Teriparatide induced delayed persistent hypercalcemia.

Nirosshan Thiruchelvam1, Jaskirat Randhawa1, Happy Sadiek1

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Case Reports in Endocrinology
|September 10, 2014
PubMed
Summary
This summary is machine-generated.

Teriparatide, a bone-building osteoporosis drug, can rarely cause delayed, persistent hypercalcemia. This rare side effect requires careful monitoring in patients undergoing treatment.

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Area of Science:

  • Endocrinology
  • Pharmacology
  • Bone Metabolism

Background:

  • Teriparatide is a recombinant parathyroid hormone (PTH) used for osteoporosis.
  • It effectively increases bone mineral density.
  • Transient hypercalcemia is a known, short-term side effect.

Purpose of the Study:

  • To report a rare case of delayed persistent hypercalcemia induced by teriparatide.
  • To highlight a potential, uncommon adverse event associated with teriparatide therapy.

Main Methods:

  • Case report detailing patient presentation and clinical course.
  • Review of teriparatide's known side effect profile.

Main Results:

  • The patient experienced delayed and persistent hypercalcemia after teriparatide administration.
  • This contrasts with the typically transient nature of teriparatide-induced hypercalcemia.

Conclusions:

  • Teriparatide can rarely lead to delayed persistent hypercalcemia.
  • This emphasizes the need for vigilance and monitoring for atypical side effects.