Light-guided localization within tissue using biocompatible surgical suture fiber as an optical waveguide
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Updated: Apr 24, 2026

Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue
Published on: October 29, 2012
Woo June Choi1, Kwan Seob Park2, Byeong Ha Lee2
1University of Washington, Department of Bioengineering, 3720 15th Avenue NE, Seattle, Washington 98195, United States.
Abstract:
In breast-conserving surgery, an optical wire is a useful surgical guiding tool to optically locate small lesions within the breast tissue. However, the use of a long silica glass fiber as the optical wire can be burdensome to patients because of its stiffness and nonbiocompatibility. We investigate the use of a biocompatible fiber for light localization in tissue. A surgical suture with a diameter of 400 μm and a few centimeters long is employed as the biocompatible optical waveguide to transport the visible laser light to the inner tissue site. Optical location is confirmed with glow ball-like red laser illumination at the tip of the suture embedded within a fresh chicken breast tissue. Effective optical power coupling to the suture is made by using a double-cladding fiber coupler. From this preliminary result, we realize practical light localization with biopolymer waveguides.

