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Updated: Apr 24, 2026
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Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
442
Craniostenosis: a neurosurgeon's perspective
Chidambaram Balasubramaniam1, Santosh Mohan Rao, Kalyanaraman Subramaniam
1From the *Kanchi Kamakoti Childs Trust Hospital, Chennai, India.
The Journal of Craniofacial Surgery
|September 10, 2014
Summary
Craniosynostosis, a condition affecting skull development in children, is increasingly recognized in India. This review discusses clinical, genetic, and surgical management challenges, drawing on over 20 years of experience.
Area of Science:
- Pediatric Neurosurgery
- Craniofacial Surgery
- Genetics
Background:
- Craniosynostosis is increasingly identified and managed in Indian pediatric neurosurgery departments.
- Management approaches vary, with established protocols in specialized units but developing practices elsewhere.
- Misconceptions persist regarding clinical presentation, genetic factors, and surgical indications for craniosynostosis.
Purpose of the Study:
- To discuss the clinical, genetic, and management aspects of craniosynostosis in the Indian context.
- To highlight the challenges and evolving landscape of craniosynostosis treatment.
- To share insights from over two decades of clinical experience.
Main Methods:
- Review of clinical experience spanning over 20 years in treating craniosynostosis.
- Discussion of challenges encountered in patient management.
- Analysis of existing literature and clinical practices.
Main Results:
- Craniosynostosis diagnosis and management are growing areas in Indian pediatric neurosurgery.
- Significant variations exist in the level of expertise and established management protocols across departments.
- Persistent misconceptions regarding the condition's genetics and appropriate surgical interventions require clarification.
Conclusions:
- Effective management of craniosynostosis requires addressing clinical, genetic, and surgical complexities.
- Standardized protocols and education are crucial to overcome management challenges.
- Continued experience sharing is vital for advancing pediatric neurosurgical care for craniosynostosis.
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