Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diagnostic epidural opioid technique.

J S Ellis1, S Ramamurthy, L S Schoenfeld

  • 1Department of Anesthesiology, Wilford Hall Air Force Medical Center, Lackland Air Force Base, San Antonio, Texas.

The Clinical Journal of Pain
|September 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Avelumab first-line maintenance for advanced urothelial carcinoma: long-term outcomes from the JAVELIN Bladder 100 trial in patients with high body mass index or diabetes mellitus.

ESMO open·2026
Same author

Search for Axion Dark Matter from 1.1 to 1.3 GHz with ADMX.

Physical review letters·2025
Same author

Safety, Pharmacokinetics, and Acceptability of a Tenofovir Rectal Microbicide Douche Among Young Men Who Have Sex With Men: The DREAM ATN Study (ATN 163).

The Journal of infectious diseases·2025
Same author

ADMX Axion Dark Matter Bounds around 3.3  μeV with Dine-Fischler-Srednicki-Zhitnitsky Discovery Ability.

Physical review letters·2025
Same author

Avelumab first-line maintenance for advanced urothelial carcinoma: long-term outcomes from the JAVELIN Bladder 100 trial in older patients.

ESMO open·2025
Same author

Avelumab + axitinib versus sunitinib as first-line treatment for patients with advanced renal cell carcinoma: final analysis of the phase III JAVELIN Renal 101 trial.

Annals of oncology : official journal of the European Society for Medical Oncology·2024

Chronic pain patients responding to lidocaine but not fentanyl may have learned pain responses. This suggests diagnostic opioid techniques could improve chronic pain diagnosis.

Area of Science:

  • Anesthesiology
  • Pain Medicine
  • Psychology

Background:

  • Diagnostic epidural blocks are used to manage chronic pain.
  • Patient responses to epidural solutions can vary significantly.

Purpose of the Study:

  • To investigate patient responses to epidural saline, fentanyl, and lidocaine.
  • To identify characteristics of patients who respond to lidocaine but not fentanyl.

Main Methods:

  • 27 chronic pain patients received sequential epidural blocks with saline, fentanyl, and lidocaine.
  • Patients were categorized into four groups based on their pain relief response.
  • Groups were compared using demographic and clinical variables.

Main Results:

Related Experiment Videos

  • The lidocaine response group (LRG) had a significantly longer average duration of pain.
  • LRG patients did not achieve pain relief with epidural fentanyl.
  • No significant differences were found in other demographic or clinical factors.

    • Conclusions:

    • LRG patients may represent a subset of operant or learned pain patients.
    • Failure to respond to fentanyl might indicate a learned association between sensory input and pain.
    • Diagnostic opioid techniques may be refined for more sensitive chronic pain diagnosis.