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An explanation of the stability of the incidence of inborn defects
Reproductive Toxicology (Elmsford, N.Y.)
|January 1, 1989
Abstract:
We propose a mathematical model for the malformation incidence in a population. The model is based on the assumption that malformations occur in a narrow range of embryotoxic doses for a given toxin and that this range varies in the population. Using this assumption, we exhibit malformation incidence curves which are in qualitative agreement with experimental data.