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A case report: indomethacin resistance hemicrania continua or a new entity?

Ozlem Coşkun1, Serap Uçler2, Ruhsen Ocal3

  • 1Department of Neurology, Ministry of Health Ankara Training and Hospital, Ankara, Turkey. oecoskun@yahoo.com.

Agri : Agri (Algoloji) Dernegi'Nin Yayin Organidir = the Journal of the Turkish Society of Algology
|September 11, 2014
PubMed

Insights

Hemicrania continua (HC) is a rare headache disorder. This case report highlights pregabalin as a potential treatment for patients with indomethacin-resistant HC.

Area of Science:

  • Neurology
  • Headache Medicine

Background:

  • Hemicrania continua (HC) is a rare primary headache disorder characterized by continuous unilateral headaches with superimposed exacerbations.
  • Diagnostic criteria for HC mandate a complete response to indomethacin treatment.

Observation:

  • This case report details a patient with HC who exhibited resistance to indomethacin therapy.
  • The patient experienced significant relief from headache symptoms upon initiation of pregabalin treatment.

Findings:

  • Indomethacin resistance does not exclude the diagnosis of Hemicrania continua.
  • Pregabalin demonstrated efficacy in managing HC symptoms in an indomethacin-resistant patient.

Implications:

  • Pregabalin represents a potential therapeutic option for managing Hemicrania continua in cases of indomethacin resistance.
  • This finding may broaden treatment strategies for patients with refractory HC.
  • Further research is warranted to confirm the efficacy and safety of pregabalin for HC.

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